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Telomerase reactivation reverses tissue ... - Nature

Loss of telomeres, the protective tips on the ends of chromosomes, causes tissue atrophy and other damage. A growing body of evidence points to telomere defects as a driver of age-associated organ ...

Pathways linking biodiversity to human health: A ...

Exposure may also differ markedly in environments with different elements of biodiversity and with the behavior (Methorst et al., 2020) or occupation of individuals (e.g. farmers in rural areas or in the tropics may be exposed to more potentially dangerous wildlife than city dwellers in the Global North) (Covert and Langley, 2002, Fontoura ...

Robust predictions of specialized metabolism genes ... - …

Specialized metabolites are critical for plant–environment interactions, e.g., attracting pollinators or defending against herbivores, and are important sources of plant-based pharmaceuticals. However, it is unclear what proportion …

More Than a Mere Student - Johns Hopkins University

May 1, 1885, was typical: Adams called the meeting to order at 8:10 p.m.; 12 members gathered around the stately table, with Wilson diligently taking notes as official secretary. A student read a paper on the Puritan colony in …

Health-promoting effects of bovine colostrum in Type 2 ...

Bovine colostrum (BC) has been reported to enhance immune function, reduce fat accumulation and facilitate the movement of glucose to the muscle. However, very few attempts have been made to examine its anti-diabetic effects in diabetes patients. The aim of this study was to evaluate whether BC decr …

India - COVID-19 Overview - Johns Hopkins Coronavirus ...

India - COVID New Cases, Deaths, Testing Data - Johns Hopkins Coronavirus Resource Center

e new england journal o medicine

e new england journal o medicine n engl j med 383;19 nejm November 5, 2020 1813 established in 1812 November 5, 2020 vol. 383 no. 19 The authors' full names, academic de-grees, and ...

Social network determinants of depression

The etiology of depression has long been thought to include social environmental factors. To quantitatively explore the novel possibility of person-to-person spread and network-level determination of depressive symptoms, analyses were performed on a densely interconnected social network of 12 067 people assessed repeatedly over 32 years as part of the Framingham …

The influence of higher protein intake and greater eating ...

The purpose of this study was to determine the effects of dietary protein intake and eating frequency on perceived appetite, satiety, and hormonal responses in overweight/obese men. Thirteen men (age 51 +/- 4 years; BMI 31.3 +/- 0.8 kg/m(2)) consumed eucaloric diets containing normal protein (79 +/- …

e new england journal o medicine

published on May 22, 2020, at NEJM. This article was published on October 8, 2020, and updated on October 9, 2020, at NEJM. N Engl J Med 2020;383:1813-26. DOI: 10.1056/NEJMoa2007764

Experimental evidence of massive-scale emotional ... - PNAS

We show, via a massive ( N = 689,003) experiment on Facebook, that emotional states can be transferred to others via emotional contagion, leading people to experience the same emotions without their awareness. We provide …

Intensive lifestyle changes for reversal of coronary heart ...

Context: The Lifestyle Heart Trial demonstrated that intensive lifestyle changes may lead to regression of coronary atherosclerosis after 1 year. Objectives: To determine the feasibility of patients to sustain intensive lifestyle changes for a total of 5 years and the effects of these lifestyle changes (without lipid-lowering drugs) on coronary heart disease.

Examining the effects of birth order on personality - PNAS

The question of whether a person's position among siblings has a lasting impact on that person's life course has fascinated both the scientific community and the general public for >100 years. By combining large datasets from three national panels, we confirmed the effect that firstborns score higher on objectively measured intelligence and additionally found a similar …

Meal replacement with mixed rice is more effective than ...

The physiologic consequences of using white rice or mixed rice were evaluated in overweight Korean women (body mass index > or = 25 kg/m(2)) over a period of 6 weeks. Forty women between 20 and 35 years of age were randomly divided into 2 groups who consumed 1 of 2 low-energy meal replacements co …

Climate change may alter human physical activity patterns ...

Climate change may reduce economic output 24, amplify rates of conflict 31, produce psychological distress 54, increase exposure to the social effects of …

Putting feelings into words: affect labeling disrupts ...

Putting feelings into words (affect labeling) has long been thought to help manage negative emotional experiences; however, the mechanisms by which affect labeling produces this benefit remain largely unknown. Recent neuroimaging studies suggest a possible neurocognitive pathway for this process, bu …

Asymptomatic SARS-CoV-2 infection: A systematic review …

Asymptomatic infections have been widely reported for COVID-19. However, many studies do not distinguish between the presymptomatic stage and truly asymptomatic infections. We conducted a systematic review and meta-analysis of COVID-19 literature reporting laboratory-confirmed infections to determine the burden of asymptomatic infections and removed index …

Linkages among climate change, crop yields and ... - PNAS

Climate change is expected to cause mass human migration, including immigration across international borders. This study quantitatively examines the linkages among variations in climate, agricultural yields, and people's migration responses by using an instrumental variables approach. Our method allows us to identify the relationship between crop yields and migration …

More Than a Mere Student - Johns Hopkins University

May 1, 1885, was typical: Adams called the meeting to order at 8:10 p.m.; 12 members gathered around the stately table, with Wilson diligently taking notes as official secretary. A student read a paper on the Puritan colony in colonial Annapolis, then Adams digressed about how the family of Mr. Johns Hopkins may have lived in that very colony.

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The Spread of Obesity in a Large Social Network over 32 ...

Nicholas A. Christakis, M.D., Ph.D., M.P.H., and James H. Fowler, Ph.D. The prevalence of obesity has increased substantially over the past 30 years. We performed a quantitative analysis of the ...

Sugar-sweetened beverage intake in adulthood and ... - Gut

Objective Sugar-sweetened beverage (SSB) consumption had substantially increased across successive US birth cohorts until 2000, and adolescents and young adults under age 50 years have the highest consumption. However, the link between SSBs and early-onset colorectal cancer (EO-CRC) remains unexamined. Design In the Nurses' Health Study II (1991–2015), we …

(PDF) Expressive Writing, Emotional Upheavals, and Health

One of the popular appeals of the expressive. writing paradigm is that is sounds almost magical. W rite for 15 minutes a day for three days (a. …

Cardiac Arrest during Long-Distance Running Races

original article The new engl and journal of medicine 130 n engl j med 366;2 nejm january 12, 2012 Cardiac Arrest during Long-Distance Running Races Jonathan H. Kim, M.D., Rajeev Malhotra, M.D ...

(PDF) Nghiên cứu tổ hợp chất chỉ điểm sinh học: vWF ...

Mục tiêu: Khảo sát nồng độ, đánh giá giá trị chẩn đoán và tiên lượng của tổ hợp chất chỉ điểm sinh học vWF, VCAM-1, MCP-1, D-Dimer ở bệnh nhân nhồi máu não cấp. Đối tương và phương pháp: Một nghiên cứu mô tả cắt ngang, có so sánh và đối chiếu nhóm

Sirtuin signaling in cellular senescence and aging

Sirtuin in cellular senescence. Cellular senescence is a physiological phenotype aimed at permanent cell cycle arrest, and is morphologically identified as flattening, increased size of nucleus and nucleoli, and the appearance of vacuoles in the cytoplasm ().In addition, several biomarkers developed for cellular senescence are targeted towards the senescence …

Hypolipidemic and Antioxidant Effects of Dandelion ...

1. Introduction. Atherosclerotic disease causes over 19 million deaths annually, yet our understanding of the fundamental aspects of the genesis of the disease remains incomplete [1,2].Several studies have shown that an increased dietary intake of cholesterol results in hypercholesterolemia, which is known to eventually generate atherosclerosis and enhance the …

Pharmacological effects of Radix Angelica Sinensis ...

Radix Angelica Sinensis, the dried root of Angelica sinensis (Danggui), is a herb used in Chinese medicine to enrich blood, promote blood circulation and modulate the immune system.It is also used to treat chronic constipation of the elderly and debilitated as well as menstrual disorders. Research has demonstrated that Danggui and its active ingredients, as …

Consumption of 85% cocoa dark chocolate improves …

In addition, the results may be subject to response bias since mood status was self-reported by the participants, although the PANAS test used in the present study is widely used and its reliability and validity have been well-demonstrated [53,54]. Finally, the underlying mechanism by which gut bacteria affected mood status is unclear.